Advertisement

Cerenia for Dogs: Uses, How It Works, and Side Effects

Complete guide to Cerenia for dogs: understanding motion sickness relief and nausea prevention.

By Medha deb
Created on

Cerenia for Dogs: What It’s Used For, How It Works and Side Effects

Motion sickness and nausea can significantly impact your dog’s quality of life, particularly during car rides or when dealing with digestive issues. Fortunately, medications like Cerenia® can help combat nausea and vomiting in dogs, allowing your pup to enjoy their travels and daily activities more comfortably. Cerenia® (maropitant citrate) is an FDA-approved antiemetic medication that’s used to prevent vomiting caused by motion sickness, such as car sickness, or a new or sudden onset of vomiting (acute vomiting) due to other causes. We consulted with veterinarians to provide comprehensive information about Cerenia® for dogs, including how it works, administration methods, potential side effects, and important risk factors.

What Is Cerenia®, and How Is It Used in Dogs?

Cerenia® (maropitant citrate) is an FDA-approved antiemetic medication that’s used to prevent vomiting caused by motion sickness such as car sickness or a new or sudden onset of vomiting (acute vomiting) due to other causes. Motion sickness is surprisingly common in dogs, with research showing that the problem extends beyond just nausea and vomiting during car rides.

In a 2012 study of dogs riding in cars, researchers found that 24.5% frequently experience excessive drooling (hypersalivation) and 18% frequently vomit. This can make travel stressful for both pets and their owners. Beyond motion sickness, a veterinarian might prescribe Cerenia® due to acute vomiting triggered by various medical conditions, including:

– Eating something that causes tummy upset (dietary indiscretion)- Nausea after anesthesia or surgery (post-operative)- Inflammatory bowel disease- Gastroenteritis- Chemotherapy side effects- Acid reflux- Internal issues such as kidney disease or liver disease

According to veterinary professionals, Cerenia® is a very commonly used medication for preventing motion sickness and vomiting in dogs. The medication has also been found to have some anti-coughing properties, so some vets prescribe Cerenia® off-label for collapsing trachea and other conditions that trigger coughing.

Can Cerenia® Be Used for Puppies?

One of the great advantages of Cerenia® is its availability for young dogs. Cerenia® can be given to puppies 2 months and older to prevent acute vomiting and to puppies 4 months and older to prevent vomiting from car sickness. This is good news, as many vets agree that puppies tend to experience car sickness more frequently than older dogs. Additionally, puppies are often new to the experience of car rides, which can increase their anxiety and stress, further contributing to nausea.

How Does Cerenia® Work?

To understand how Cerenia® can help prevent vomiting in dogs, you first need to understand the vomit control center of the brain. This area, known as the emetic center, is responsible for detecting signals that trigger nausea and vomiting. Creating a “vomit signal” involves a neurotransmitter called substance P binding to neurokinin-1 (NK1) receptors in the brain.

Cerenia® works by blocking these NK1 receptors, so that substance P can’t bind to them. As a result, the brain is unable to get the “become nauseated and throw up” memo, and your pup remains nausea-free. By acting on the central nervous system rather than the gastrointestinal system directly, Cerenia® provides effective relief regardless of what’s causing the nausea or vomiting. This mechanism makes it effective for motion sickness, post-operative nausea, chemotherapy side effects, and vomiting from various medical conditions.

How Do You Give Your Dog Cerenia®?

Cerenia® is typically given by mouth as a tablet, or a veterinarian will sometimes give Cerenia® as an injection under the dog’s skin. The choice between oral and injectable forms often depends on your dog’s specific condition, the severity of symptoms, and your veterinarian’s recommendation.

Whether given as an oral tablet or by injection, Cerenia® takes effect in one to two hours and it is effective for about 24 hours. This relatively quick action and long duration of effectiveness make it a practical choice for managing both acute episodes and preventive care.

What Are the Side Effects of Cerenia® for Dogs?

While Cerenia® is generally safe and effective for managing nausea and vomiting in dogs, it can have some potential side effects. It’s essential to be aware of these so you can consult your veterinarian if any issues arise. Although still rare, the most common side effects include:

– Excessive drooling- Diarrhea- Decreased appetite- Vomiting- Injection site reaction (swelling, pain upon injection)

Additionally, Cerenia® should not be used in puppies under 4 months old when using it to prevent motion sickness, as the higher dose required to prevent motion sickness has been associated with low blood cell counts (bone marrow suppression). This is an important consideration when treating young animals, and it’s why following your veterinarian’s guidance on age-appropriate dosing is critical.

Cerenia® Effectiveness and Duration

Cerenia® has been demonstrated to be highly effective in laboratory studies for preventing acute vomiting and motion sickness. The medication is now considered the first choice for motion sickness prevention in dogs. One significant advantage of Cerenia® is that it works equally well whether the vomiting is caused by motion sickness or systemic illness, making it a versatile treatment option.

The medication’s effectiveness lasts approximately 24 hours in dogs with healthy livers. This duration makes it convenient for managing motion sickness during travel or for post-operative care, as you typically need just one dose per day.

Additional Benefits Beyond Nausea Control

Beyond its primary use as an antiemetic, Cerenia® has been shown to offer additional clinical benefits. Research suggests that Cerenia® may also act as a mild pain control medication and is often used as an anesthetic pre-medication. This multi-functional capability makes it particularly valuable in perioperative settings, where managing both pain and nausea is essential for a smooth recovery.

Frequently Asked Questions About Cerenia®

Is Cerenia® an appetite stimulant?

Cerenia® itself is not an appetite stimulant. However, because it reduces nausea and vomiting, it can help restore your dog’s appetite by making them feel better and more willing to eat.

Can my dog eat after taking Cerenia®?

Yes, your dog can eat after taking Cerenia®. If you give your dog Cerenia® for motion sickness before traveling, it’s best to avoid giving them a full meal. However, a small meal is fine. This helps prevent additional stomach upset while still providing some nutrition.

What are the signs that my dog might need Cerenia®?

Signs that your dog might need Cerenia® include motion sickness during car rides, which can include restlessness, drooling, or vomiting. Additionally, if your dog is recovering from surgery or anesthesia, or if they’re experiencing acute vomiting from various causes, your veterinarian may recommend Cerenia® as part of their treatment plan.

How quickly does Cerenia® work?

Cerenia® takes effect in one to two hours after administration, whether given orally or by injection. This relatively quick action makes it suitable for preventive use before car trips or other situations likely to trigger motion sickness.

How long does Cerenia® last?

Cerenia® is effective for approximately 24 hours in dogs with healthy livers. This means you typically only need to administer one dose per day for ongoing management.

Can Cerenia® be used long-term?

While Cerenia® is safe for most dogs, the medication should not be given to dogs to prevent motion sickness for more than 2 days in a row. If your dog needs additional nausea control beyond this period, consult with your veterinarian about alternative approaches or underlying conditions that may need additional investigation.

When to Contact Your Veterinarian

If your dog experiences any unusual symptoms after receiving Cerenia®, or if side effects persist or worsen, contact your veterinarian immediately. Similarly, if your dog’s vomiting or nausea doesn’t improve with Cerenia® treatment, your veterinarian may need to investigate underlying conditions that could be contributing to these symptoms. Remember that while Cerenia® is effective at managing nausea and vomiting, it works on symptom relief and doesn’t treat or resolve underlying gut problems or systemic issues.

The Bottom Line

Cerenia® for dogs is a safe, fast-acting medication used to reduce acute nausea and vomiting caused by a variety of issues, from motion sickness to post-operative recovery. Like any prescription medication, it should be given under the supervision of a veterinarian. If your dog experiences motion sickness, travels frequently, or faces surgery, talk to your veterinarian to see if Cerenia® could be a solution to improve their comfort and quality of life.

References

  1. Cerenia (Maropitant Citrate) for Dogs: Uses, Side Effects, and More — GoodRx Pet Health. 2024. https://www.goodrx.com/pet-health/dog/cerenia-for-dogs
  2. Cerenia® for Dogs: What It’s Used For, How It Works and Side Effects — Chewy Education. 2024. https://www.chewy.com/education/dog/health-and-wellness/cerenia-for-dogs
  3. Cerenia (Maropitant) for Dogs: Uses, Side Effects, and Alternatives — American Kennel Club. 2024. https://www.akc.org/expert-advice/health/cerenia-for-dogs/
  4. Maropitant Citrate — VCA Animal Hospitals. 2024. https://vcahospitals.com/know-your-pet/maropitant-citrate
  5. Perioperative Prevention Benefits of Cerenia — Zoetis U.S. 2024. https://www.zoetisus.com/products/petcare/cerenia
Medha Deb is an editor with a master's degree in Applied Linguistics from the University of Hyderabad. She believes that her qualification has helped her develop a deep understanding of language and its application in various contexts.

Read full bio of medha deb